

They’re reformulate it and call it something new. They’ll still sell amlodipine for blood pressure.
They’re reformulate it and call it something new. They’ll still sell amlodipine for blood pressure.
This is really interesting. As I was reading the article I was wondering how they were going to wring money out of it, as amlodipine is off patent. Then I got to this part:
“While amlodipine shows promise in preclinical models, it is not currently suitable for use in ADHD in its marketed form,” Karlsson noted. “Further optimization through chemical modification is necessary to enhance CNS selectivity and ensure a favorable therapeutic index in the context of ADHD.”
Classic big pharma. Slightly tweak an existing drug in an insignificant way so that you can get a new patent on it and charge exorbitant prices.
The Kobo Clara supports libby and also DRM free ebooks. Display is clear and battery life is good.
It used to be that phone technology improved relatively quickly, and a 2 year old phone was significantly worse than the latest and greatest. Now, not so much. I use a Pixel 6 Pro running Graphene OS, and I don’t feel like I’m missing out on the latest tech. The camera is great, certainly more than good enough for me, and the phone is responsive and does everything I need it to do, and it’s 3+ generations old. I see no need to spend $1000+ on a new phone.